Formulation of poorly water-soluble drugs via coacervation – A pilot study using febantel
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چکیده
منابع مشابه
Formulation of poorly water-soluble drugs via coacervation--a pilot study using febantel.
In this study, febantel was dissolved under increased temperature in a nonionic surfactant Lutrol L44® and subsequently mixed into an aqueous maltodextrin solution. After 8h under static conditions, coacervation or phase separation took place. (1)H NMR spectra and HPLC analysis showed that the upper phase contained mainly all febantel, while no febantel was detected in the lower phase. Fluoresc...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2013
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2013.07.006